D Nikhil Venkata Reddy 1801006038 Roll no 41

79 y/o male with Recurrent CVA and left hemiplegia with Aspiration pneumonia and seizures disorder

- March 16, 2023

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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan


COMPLAINTS AND DURATION

A 79 y/o male was brought to casuality with c/o cough since 20 days , 
fever since 10 days
difficulty in swallowing and h/o Aspiration pneumonia since one month
C/o altered sensorium since 3 days

HISTORY OF PRESENTING ILLNESS 

Patient was apparently asymptomatic 20days back then he developed cough insidious in onset and gradually progressive. PRODUCTIVE but patient is not able to spit it out. 
Difficulty in swallowing.

Series of events as follows

* Patient developed cough and cold on 25th February 2023
* Took treatment for cold on March 1st
* There were increased secretions on  March 3rd but the patient was unable to spit it out
* Admitted in hospital from March 5th to March 10th and cleared secretions through suction.


H/O cough on intake of liquids.
H/O change of voice since 20 days, insidious, hoarse in character and  SLURRING OF SPEECH is present
No H/O difficulty in breathing, breathlessness, hemoptysis. 

Fever since 10 days - High grade. 
O/E Chills and rigors + (38 spikes).
N/H/O Vomiting, Chest pain, Loose stools.

7 YEARS AGO(2016)
He developed head ache at around afternoon 2pm followed by vomtings and left hand itching and weakness.

PATIENT was awake on that night due to left hand weakness and itching

NEXT DAY 
MORNING they took him to hospital 
Patient can lift his hand 
But unable to hold objects

AFTER 3 DAYS
PATIENT became left sided hemiplegia.

MRI REPORT shows 3 INFARCTS

Patient stayed for 40 days in hospital and there was no improvement and discharged.

He took liquids for 3 months because patient is unable to eat solid foods. He then slowing started eating solid foods.

AFTER 1 YEAR (2017)
vomitings 
Fever 
Shivering for 3 days
 
Diagnosed with urinary tract infection 
Took treatment (antibiotics) for 5 days and it was resolved

AFTER 3 YEARS(2020)

Cough for 2 days 
Fever on 2 nd day
Diagnosed with covid
Infected with COVID for 1st time and resolved

After 1 year(2021)
 He was Diagnosed with COVID for 2nd time and resolved 

1 YEARS back (2022)
He got seizures for 5 min and they took him to the hospital.

He got Typhoid fever 2times 
1st time resolved in 7days
2nd time resolved in 9 days


79 Year old male who is a father of 4 children ( 2 sons and 2 daughters) used to run a shop ( kirana shop) for about 18 years.He stopped looking after his shop from 2006 and he was looked after by his sons. 

He was non alcoholic,non smoker.

10 years ago , patient developed lesions on his both foot and went to the doctor and found to have diabetes and started on medication and after 1 year ,with regular check up he was found to be Hypertensive and started on antihypertensive medication.

From 7 years onwards , patient was bedridden with foleys ( changed every 15 days ) and physiotherapy was done by his attenders daily, but there was no such improvement

PAST HISTORY  

Patient is a k/c/o Hypertension and type 2 diabetes since past 10years for which he is on medications I.e tab TELMA AM 40mg andTab zoryl. 

PERSONAL HISTORY 

Appetite - lost
Mixed - Diet
Bowel - Constipated, 
Bladder - Regular 
No known allergies and Addictions. i.e non alcoholic and non smoker

Family History
Not significant 

Treatment history   
 
Tab TELMA AM 40mg po/od since past 10years
Tab zoryl mv , po/od
Tab levipil 500mg since 2 years
Thyronorm 25mcg. Since5 years


GENERAL EXAMINATION 

On examination patient is arousable but not oriented.
Patient is not cooperative mostly. 
-PALLOR: PRESENT
NO PEDAL EDEMA, ICTERUS, CYANOSIS, CLUBBING, LYMPHADENOPATHY

VITALS ON ADMISSION 

Pulse Rate -b90 BPM
BP- 140/80MM HG
Respiratory Rate - 22 CPM
SPO2- 98%
GRBS - 183mg/dl

SYSTEMIC EXAMINATION

Respiratory 

Inspection : respiratory movements equal on both sides
Trachea is  central
palpation apical impulse in left 5th intercostal space 
Auscultation : Crepitations on auscultation
Percussion- BAE+
Tachypnea is present 
CNS 

PATIENT is unconscious incoherent uncooperative

HIGHER MENTAL FUNCTIONS- cannot be elecited
Speech 
Behaviour
Memory
Intelligence
Lobar functions


B/L PUPILS - NORMAL SIZE AND REACTIVE TO LIGHT

NO SIGNS OF MENINGEAL IRRITATION

CRANIAL NERVES 
 2nd cranial nerve 
Visual acuity is decreased on left side
3rd 4th 6th pupillary reflex present

 SENSORY SYSTEM- cannot be elicited 

Spinothalamic sensation
Crude touch
Pain  
Temperature

Dorsal column sensation
Fine touch 
Vibration
Propioception

Cortical sensation
Two point discrimination
Tactile localisation
Stereognosis
Graphathesia


MOTOR EXAMINATION
                 
                       Right                          Left

                    UL LL                          UL LL

  BULK    Normal Normal            Reduced                            
 TONE     Normal                      Hypotonia

 POWER     Could not be elicited
SUPERFICIAL REFLEXES

plantar reflex  
Left side babinski sign positive


  DEEP REFLEXES

BICEPS, TRICEPS, SUPINATOR, KNEE ANKLE 
















CEREBELLAR EXAMINATION cannot be elicited

  Finger nose test

  Heel knee test 

  Dysdiadochokinesia

  Dysmetria
hypotonia with pendular knee jerk present.

  Intention tremor present.

  Rebound phenomenon .

  Nystagmus

  Titubation

  Speech

  Rhombergs test

SIGNS OF MENINGEAL IRRITATION: absent

GAIT
 patient unable to walk

CVS
AUSCULTATION: S1S2 +,NO MURMURS

P/A
INSPECTION: UMBILICUS IS CENTRAL AND INVERTED, ALL QUADRANTS MOVING EQUALLY WITH RESPIRATION,NO SCARS,SINUSES, ENGORGED VEINS, PULSATIONS

AUSCULTATION
No bowel sounds heard
bed sores
C/O asymptomatic lesions all over the body since 2 months
H/O application of unknown topical medications used
O/E multiple hyperpigmented Macclesfield present all over the body with scaly lesions over the upper back
•Diffuse xerosispresent
• single ulcer of size 1.5x1.5 cms (approx) over the back.
Diagnosis SENILE XEROSIS + post inflammatory hyperpigmentation.
( +? TROPHIC ULCER )OBSERVATIONS:

• Large area of encephaolomalacia in right occipito -temporo lobes and righ parietal lobes.
• Prominence of sulci and cisterns. 
• Bilateral periventricular hyperintensity.
• Rest of the Cerebral parenchyma shows normal gray/white matter differentiation.
• Basal ganglia and Thalami are normal.
• Brain stem normal.
• Cranio-vertebral and Cervico-medullary junctions are normal.
• Sella, pituitary and parasellar regions are normal. Stalk and hypothalamus are normal. Posterior pituitary bright spot is normal.
• No evidence of abnormal calcifications, vascular anomalies on SWI sequences.
IMPRESSION:
• Large area of encephalomalacia in right occipito-temporo lobes and right parietal lobes - sequelae of old infarct.
• Diffuse cerebral atrophy. Chronic small vessel ischemia.
Note: Poor quality of images due to motion artefacts

CUE 

AFB-TRACE
PUS CELLS -2-4
EPITHELIAL CELLS -2-3
LFT 

INVESTIGATIONS

Anti HCV antibodies rapid - Nonreactive
Blood urea - 30mg/dl
HBA1C- 6.7%
HbsAg rapid - Negative
HIV 1/2 RAPID TEST - NON REACTIVE
TOTAL BILIRUBIN -0.81mg/dl(normal-0 to 1mg/dl)
Direct bilirubin-0.17mg/dl(0 to 0.2mg /dl)
Serum creatinine -0.9 mg/dl (0.8 to 1.3 mg /dl)


ABG

Ph 7.51
PCO2 29.5mmhg
Po2 67.5 mmhg


ELECTROLYTES

Sodium 135meq/l
Potassium 3.5 meq/l
Chloride 98meq/l
Calcium -1.06 mmol/l

PROVISIONAL DIAGNOSIS 

 Recurrent CVA with Hypertension, T2 DM, seizures disorder. 

TREATMENT 

1) TAB ECOSPRIN 150 mg RT/OD
 2) TAB CLOPIDOGREL 75 MG RT/OD 
3) TAB ATORVAS 20 MG RT/OD
4) NEBULISATION - 3% NS                              5)CHEST PHYSIOTHERAPY.
6) RT FEEDS 100 ML WATER 2nd HRLY
                        50 ML Milk 2nd HRLY.
8) TAB. THYRONORM 25MCG RT/OD
9) TAB. LEVIPiL 

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